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Bio Essence

Essences · Uncommon

Bio Essence

Sells for: 25 coins
Stack size: 250
Rarity: Uncommon
Used in: 16 items

Counts as

Any Tier 1 Essence

How to make it (6 recipes)

Recipe 1

Slime Essence×2

Crafted atTransmutation Station Recipe Open in crafting calculator

Recipe 2

Blood Essence×2

Crafted atTransmutation Station Recipe Open in crafting calculator

Recipe 3

Spider Essence×2

Crafted atTransmutation Station Recipe Open in crafting calculator

Recipe 4

Shadow Essence×3

Crafted atTransmutation Station Recipe Open in crafting calculator

Recipe 5

Cryo Essence×3

Crafted atTransmutation Station Recipe Open in crafting calculator

Recipe 6

Primordial Essence×3

Crafted atTransmutation Station Recipe Open in crafting calculator

Used in (16)

Transmutation Station×10via Any Tier 1 Essence
Potion Bag×5
Ammo Bag×5
Shadow Essence×3
Cryo Essence×3
Primordial Essence×3
Aged Champion Shield×20
Swamp Dweller Staff×20
Druids Greatbow×20
Venom Shower×20
Venom Slasher×20
Living Shotty×20
Swamps Grasp×20
Fallen Anvil×10via Any Tier 1 Essence
Fallen Alchemy Table×10via Any Tier 1 Essence
Deep Swamp Rock Bio Essence×1

What can I make with it? Open the crafting calculator

Home/Necesse/Materials

Materials

What each ore, bar and drop is used for

Data updated 26 Oct 2026

Overview How Materials Work All MaterialsBosses Weapons Armor Trinkets Crafting Recipes Materials Mobs Biomes Settlers Food & Potions Fish Enchantments Furniture AchievementsWeapon Tier List Armor Tier List Trinket Tier List Boss Progression Crafting Calculator Damage Calculator

NecesseMaterials

Overview How Materials Work All Materials

All Guides

Bosses Weapons Armor Trinkets Crafting Recipes Materials Mobs Biomes Settlers Food & Potions Fish Enchantments Furniture Achievements

Tools

Weapon Tier List Armor Tier List Trinket Tier List Boss Progression Crafting Calculator Damage Calculator

Overview

Only 32 of the 130 materials come from a recipe. You mine, chop or loot the rest, and Dryad Log is the busiest, going into 142 items.

How Materials Work

Ores and Bars · Ingredient Groups

Ores and Bars

Ore becomes a bar at the Forge. Broken tools smelt back into bars too, so scrap gear is stock.

Ingredient Groups

Logs and stones count toward Any Log and Any Stone recipes, so whichever kind you have lying around fills the slot.

All Materials

Search materials

Showing 3 of 3

Type

Rarity

Crafted

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Cryo Essence25 coinsEssences · UncommonUsed in 17 · craftable
Bio Essence25 coinsEssences · UncommonUsed in 16 · craftable
Primordial Essence25 coinsEssences · UncommonUsed in 17 · craftable