Drain Power | Slay the Spire 2 Cards

Slay the Spire 2 Cards

The STS2 card list: 577 cards across Ironclad, Silent, Defect, Regent, and Necrobinder, most with a Plus upgrade

Data from build 23811903, updated 7 Nov 2026

Five classes split Slay the Spire 2’s card pool between them, Ironclad, Silent, Defect, Regent, and Necrobinder, plus a Colorless pool anyone can draft from. Every card you draft carries one of four rarity tiers (Common, Uncommon, Rare, or Ancient), a type (Attack, Skill, or Power), and a set Energy cost. Upgrade one and it almost always flips to a Plus version, 564 of the game’s 577 cards do, usually a straight damage, Block, or cost improvement that makes an early pickup worth keeping all run. Knowing which cards have the best Plus upgrades is the difference between a card you cut turn one and one you build your deck around.

Rarity & Energy Cost

Four Rarity Tiers

Every deckbuilding card carries one of four rarities, Common, Uncommon, Rare, or Ancient. Ancient sits at the top, the rarity you see least often and the one most likely to shape a run when it turns up. That same rarity field also tags cards you don’t pick from a pool, like Basic (the Strike and Defend starters every class opens with), Curse, Status, Event, Quest, and Token. Don’t count those as a fifth tier; they’re just labels for what kind of card you’re looking at.

Energy Cost

Energy is the resource that caps how many cards you can play in a turn, and most cards cost a flat number between 0 and 9. A handful, like Cascade and Dirge, cost X instead: play one and it burns every point of Energy you have left, with the effect scaling to match. Upgrading a card to its Plus form sometimes shaves a point off the cost rather than boosting the effect, and that can matter more than the stat bump once your deck gets expensive to run.

STS2 Cards by Class

Ironclad Cards

87 cards built around Block, Strength, and Exhaust. Rares like Barricade, Demon Form, and Fiend Fire reward a deck that keeps its Block and burns through its hand.

Silent Cards

88 cards for Poison, Shivs, and cheap plays. Envenom and Fan of Knives anchor those two plans, and Grand Finale deals 60 to every enemy once your Draw Pile is empty.

Defect Cards

88 cards that channel Orbs and scale with Focus. Look at Buffer, Echo Form, and Hyperbeam, which hits everything for 28 at the cost of 3 Focus.

Regent Cards

88 cards that spend Stars and Forge. Genesis pays out 2 Stars a turn, Big Bang is a 0-cost Forge 5, and Comet deals 33 plus Weak and Vulnerable.

Necrobinder Cards

88 cards that stack Doom, add Souls, and Summon. End of Days kills anything holding Doom equal to its HP, Necro Mastery summons 5 at once, and Eradicate is an X-cost Attack with Retain.